Hi Phil,
There is no keyboard shortcut that you need to press the get the mouse working on your laptop.
1
Boot your laptop into BIOS, is the mouse working in BIOS?
2
Do other devices like a USB flash drive work if you connect them to the USB ports on your laptop?
3
Connect the USB transceiver to your laptop.
Right click your Start Button and open Device Manager.
Please provide a screenshot of that full Device Manager window.