A Microsoft file hosting and synchronization service.
Hello SG Construction,
This may be caused by OneDrive remaining stuck in the background, macOS blocking its access, or an incompatibility with your macOS version.
Open Applications > Utilities > Activity Monitor, search for OneDrive, select any OneDrive-related processes, and choose Force Quit. Then try opening OneDrive again from the Applications folder.
If it still does not open, go to System Settings > Privacy & Security > Full Disk Access and make sure OneDrive is allowed. Restart your Mac after changing this setting.
Also check whether both the Mac App Store and standalone versions are installed, as these versions can conflict. If you originally installed OneDrive from the App Store, remove that copy and install Microsoft’s standalone version instead.
You can also test OneDrive in a new Mac user profile. Go to System Settings > Users & Groups > Add User, create a temporary standard account, sign in to it, and try opening OneDrive.
If the issue continues, please share your macOS version and describe exactly what happens when you open OneDrive, including any error message. The latest OneDrive desktop app currently requires macOS 15.8 or later, so compatibility may be a factor.