Hi, @Xdjustwill
Thanks for the very thorough report, that made this easier. Short version: yes, the DPC numbers from nvlddmkm.sys are high enough to cause audio dropouts on their own, and the LiveKernelEvent 141 and Event ID 153 entries point to the same place, the NVIDIA driver stack. Also, don't chase rspLLL64.sys, that one is LatencyMon's own kernel driver, so it shows up in every report. Worth noting that stutter and DPC spikes that build up over time have been reported specifically after driver 621.01, which is the version you're on.
Here are some suggestions you can try:
Do a proper clean driver swap instead of a plain reinstall. Download DDU, boot into Safe Mode, run it with "Clean and do not restart", then install either the newer 621.14 or an older driver you know was stable (something from a few months back). Choose "Custom" > "Perform a clean installation" and skip extras like GeForce Experience/NVIDIA App while testing. A normal reinstall over the top keeps old settings and files, which is likely why it didn't change anything.
In NVIDIA Control Panel > Manage 3D Settings, set Power management mode to "Prefer maximum performance". The card dropping in and out of low power states at idle is a common source of those DPC spikes, which lines up with your crackling happening outside of games.
In Windows Settings > System > Display > Graphics > Default graphics settings, turn off Hardware-accelerated GPU scheduling and reboot.
If you're not using HDMI/DisplayPort audio, disable "NVIDIA High Definition Audio" in Device Manager under Sound, video and game controllers.
Run LatencyMon again for 10 to 15 minutes after each change so you can see which one actually moves the nvlddmkm.sys numbers.
If after the clean driver swap the 141 events still appear with the card at stock, then it's time to look at the PSU cables and RAM (run a MemTest86 pass), since a GPU timeout that survives multiple drivers usually isn't software anymore. Feel free to post the new LatencyMon results and we can go from there.