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Thanks for posting here in the Microsoft Community. I understand your concern regarding the inability to re-pair or re-sync your wireless keyboard and mouse with their USB transmitter/receiver after the connection dropped or the original dongle failed. To help us pinpoint the exact cause and find the right solution, could you share what troubleshooting steps you’ve already tried so far? like replacing the batteries, trying a different USB port, or attempting to use any specific pairing software. Additionally, if you could let us know the exact brand and model of your keyboard and mouse set, that will help us check if there is an official re-pairing tool or firmware update available for your specific hardware.