Changing Mouse Primary Left Click To Right

Question

Changing Mouse Primary Left Click To Right

Sheilah Say 20

I am trying to change my primary left click to the right button.

My O/S is Windows 10 Home and it is up to date.

The mouse is a Logitech M325.

Here's what's happening.

I go to Settings, Mouse or to Logi Options+ and change the primary button to the right button.

My primary button is now the right button.

All is good until the computer is restarted or starts up the next day and the primary button reverts back to the left button.

What I did next was open Control Panel and click Mouse. Which bring up the Mouse Properties Window.

In the Properties I change the primary button from left to right click apply and oKay.

When the window closes the primary button reverts back to left.

I contacted Logitech Support and after 45 minutes of Q&A they suggested getting in touch with Microsoft because it maybe in the operating system.

Sheilah

Sheilah Say 20 Reputation points

2026-10-21T22:33:18.1+00:00

Logitech Download Assistant, Logitech Unifying Sodtware and Loitech Mouse and Keyboard Settings,

When I set the right button for primary in Settings or Logi Options+. It will stay that way until I reboot or start my computer. Then it reverts back to left primary. The only time it will revert immediately is in the mouse properties window after it has been changed there; click apply and OK. I will do your suggestion now.

4 answers

Your answer

Sheilah Say 20 Reputation points

2026-10-21T22:33:18.1+00:00

Logitech Download Assistant, Logitech Unifying Sodtware and Loitech Mouse and Keyboard Settings,

When I set the right button for primary in Settings or Logi Options+. It will stay that way until I reboot or start my computer. Then it reverts back to left primary. The only time it will revert immediately is in the mouse properties window after it has been changed there; click apply and OK. I will do your suggestion now.

Answer 1

Horace Wiggins 535

Try the Control Panel and after you make your selection be sure to click on Apply and then OK.

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Answer 2

Sheilah Say 20

I answered your first query and in your second said I would try that name.

When I clicked Post Answer I lost the entire reply.

But I did as you suggested; disabled all logitech software at start up and re booted.

As the mouse was already on right primary. When going to the settings>mouse it was still on right primary. So I did not touch it. I am guessing that there is a conflict with the Logitech software.

I will, however, give you an update the next time, tomorrow, I start up my computer. Unless you have something else you would like me to try?

Thank you.

Sheilah

Hendrix-V 20,385 Reputation points Microsoft External Staff Moderator

2026-10-22T01:46:50.3133333+00:00
Hi Sheilah Say,

I would leave things as they are for the next normal startup. If the setting remains on Right, you can then isolate the component:

Re-enable one Logitech startup item.

Restart and check the primary button.

Repeat with each item until the behavior returns.

Windows supports enabling or disabling individual startup applications through Task Manager, so this is a practical way to narrow down which component is involved.
Sheilah Say 20 Reputation points

2026-10-22T03:10:47.19+00:00

I will let you know.
Sheilah Say 20 Reputation points

2026-10-22T20:28:13.28+00:00

I started up my computer and the right button primary stayed the right button primary. :)

Sheilah
Sheilah Say 20 Reputation points

2026-10-23T07:24:24.6033333+00:00

I'll do that.

Thank you,
Hendrix-V 20,385 Reputation points Microsoft External Staff Moderator

2026-10-23T07:37:33.8866667+00:00
Hi Sheilah Say,

Thank you for the update. Since the right button remained primary after startup with the Logitech software disabled, you can now re-enable the Logitech startup items one at a time:

Enable one Logitech startup item.

Restart the computer and check the mouse setting.

If it remains correct, enable the next item and repeat.

When the problem returns, you should have identified which Logitech component is changing the setting. You can then leave that particular startup item disabled if it is not required, or check with Logitech for an updated version.

Glad we're getting closer to identifying the cause, and thank you for working through the tests.

Answer 3

Hendrix-V 20,385 Microsoft External Staff Moderator

Hi Sheilah Say,

An additional check that you can try is to create a temporary local Windows user account and set the primary button to Right there. Restart the PC and check whether the setting remains.

If it does, that strongly narrows the problem to the original user's profile or its saved preferences rather than the mouse itself.

If the behavior continues even in another account, please let us know. That result would help narrow the next troubleshooting step without repeating the methods you have already tried.

0 comments

Answer 4

Jeronimo Fuerte 47,610 Independent Advisor

To narrow this down, could you please confirm whether you have any additional Logitech software installed, such as Logitech Options or SetPoint, alongside Logi Options+? Also, does the setting revert immediately when you change it through Windows Settings, or only after restarting when Logi Options+ is running? These details will help determine whether the problem is caused by conflicting software or Windows failing to retain the preference.

As an additional troubleshooting step, I suggest temporarily preventing Logitech's software from loading at startup. Press Ctrl + Shift + Esc, open Task Manager > Startup, locate Logi Options+ and any other Logitech configuration utilities, and select Disable. Then restart Windows, open Settings > Devices > Mouse, and change Select your primary button to Right without opening Logitech's software. Restart once more and check whether the setting remains saved. If it does, this would suggest that a Logitech background process or configuration is overriding the Windows setting. If it still reverts, Microsoft's recommended next step is a clean boot to identify possible third-party software conflicts.

https://support.microsoft.com/windows/experience/startup-boot/how-to-perform-a-clean-boot-in-windows.

Please let me know the results of the startup test to determine the next step without repeating the procedures you've already tried.

Jeronimo Fuerte 47,610 Reputation points Independent Advisor

2026-10-21T22:50:49.11+00:00

Great, please let me know what happens so I can try to help you further.
Jeronimo Fuerte 47,610 Reputation points Independent Advisor

2026-10-22T00:10:43.48+00:00

I'm glad to hear that after disabling the Logitech startup applications and restarting your computer, the right mouse button remained configured as the primary button. This is encouraging and suggests that one of the Logitech background applications may have been overriding your Windows mouse settings, although still need to confirm whether the change persists.

At this point, I don't think any additional troubleshooting is necessary until we see the results of your next startup test. Please keep the current configuration unchanged and let me know whether the right button remains the primary button when you turn on your computer tomorrow. If it does, we will have a stronger indication that the Logitech software was responsible.
Jeronimo Fuerte 47,610 Reputation points Independent Advisor

2026-10-22T23:15:52.0566667+00:00

Thank you for the update. It's encouraging that the right-click setting remained unchanged after disabling the Logitech startup programs and restarting Windows.

I suggest re-enabling the Logitech startup applications one at a time, restarting Windows after each change. This should help identify which application is responsible if the issue returns. Once identified, you can leave that particular startup application disabled while keeping the others enabled.
Jeronimo Fuerte 47,610 Reputation points Independent Advisor

2026-10-23T19:30:15.0166667+00:00

A pleasure, have a great day!