Hi @Watcharavin Apichai
Since reinstalling PowerPoint resolves the issue temporarily, but the same issue has occurred several times on the same Mac, I would first try to identify what is triggering the issue rather than repeatedly reinstalling the application.
Could you please provide the following information?
- Which version of PowerPoint are you using?
- Which macOS version is currently installed on your Mac?
- Did this issue start after a recent PowerPoint, Microsoft 365, or macOS update?
- What is the exact error message that appears when you try to open PowerPoint? If possible, please provide a screenshot of the error message with any personal or sensitive information removed.
Then, please try starting your Mac in Safe Mode and check whether the same issue occurs with PowerPoint.
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Please also test PowerPoint using a new macOS user profile. If PowerPoint works normally under the new account while the issue continues under the original account, this may indicate that the issue is related to the original user profile, preferences, or another per-user component rather than a general PowerPoint/macOS compatibility issue.
Microsoft's current list of known PowerPoint for Mac issues does not appear to include this specific recurring corruption scenario. Since reinstalling PowerPoint from the Microsoft 365 portal allows it to work normally again, the results of these tests would help narrow down whether the issue is related to the PowerPoint/macOS version combination, the macOS user profile, or something else on the affected Mac.