An integrated threat protection solution designed to detect, investigate, and respond to cyber threats across Microsoft 365 services.
It's completely up to you.
While on any given day, antivirus 'A' may beat antivirus 'B' in testing, over an extended period of time, most antivirus apps are equally good at what they do, including Microsoft Defender. So base your choice on other considerations, like which one is easier for you to understand, which one has an interface that you like, which one has better support, and which has additional features that you find useful.
Microsoft Defender can be a fine choice, but don't choose it solely or mostly because it comes from Microsoft. While it's certainly true that no one knows Windows better, no one knows any better than anyone else where and how an attacker will strike next.
Most important: Don't rely exclusively on an antivirus app to protect your computer. Traditional viruses constitute a tiny percentage of today's attacks. Most successful attackers today use techniques that are not detected by antivirus apps. That's why all of us need to keep on top of the many threats coming from the internet so we can stand a chance to avoid them.