An integrated threat protection solution designed to detect, investigate, and respond to cyber threats across Microsoft 365 services.
The two enabled extensions complete only part of setup; Microsoft Defender must also have Full Disk Access, unless those are the two entries you already enabled under that specific setting.
Complete the separate permission
- Open Apple menu → System Settings → Privacy & Security → Full Disk Access.
- Enable:
- Microsoft Defender
- Microsoft Defender Endpoint Security Extension or Microsoft Defender Extension, if shown
- Return to Privacy & Security and handle any message stating that system software requires attention:
- Select Details.
- Select both Microsoft Defender entries.
- Select OK.
- Quit Microsoft Defender, restart the Mac, and reopen Defender while signed in with the personal Microsoft account associated with your Microsoft 365 Personal or Family subscription.
System-extension approval and Full Disk Access are separate parts of Microsoft’s Mac setup procedure.^1^
Since you already checked for Webroot remnants, there is no need to repeat that check.
If those two toggles were already under Full Disk Access
Check whether macOS has activated the extensions rather than merely displaying them as enabled. Open Finder → Applications → Utilities → Terminal, then run:
mdatp health
systemextensionsctl list
mdatp health --details system_extensions
Look for:
-
healthy : true -
full_disk_access_enabled : true -
real_time_protection_available : true - Both Defender extensions showing
[activated enabled]
If an extension reports [activated waiting for user], macOS is still waiting for local approval. Return to System Settings → Privacy & Security, approve the pending Microsoft system software, and restart. Microsoft documents that an enabled-looking extension can still be installed but not approved or ready.^2^
After setup completes, verify protection from Microsoft Defender → Device details → Start scan, choose a scan type, and select Start scan.^3^
Check the macOS version if installation itself will not proceed
Select Apple menu → About This Mac. If the Mac is running macOS Ventura 13, current Defender installation packages may require a newer macOS release; a closely matching Ventura case reports that packages released from April 2026 require macOS 14 or later.^4^ In that condition, permission changes will not resolve the installer requirement—the Mac must be upgraded to a supported macOS version, if its hardware supports one.
References
- [Mac](https://support.microsoft.com/defender/installing-microsoft-defender)
- Troubleshoot Microsoft Defender for Endpoint system extensions on macOS
- How to start a scan for viruses or malware in Microsoft Defender | Microsoft Support
- Window Defender not running on MacOS Ventura 13.7.8 - Microsoft Q&A