An integrated threat protection solution designed to detect, investigate, and respond to cyber threats across Microsoft 365 services.
Hi, @Neil Hodge
Please check "Settings" > "Apps" > "Installed apps" for any preinstalled third-party antivirus, such as McAfee or Norton. If you intend to use Defender as your antivirus, uninstall that software and restart your PC.
If the issue persists, please reinstall the Microsoft Defender app:
- Open "Start", search for "Microsoft Defender", right-click it and select "Uninstall".
- Reinstall it from the Microsoft Store.
- Open the app and sign in with the Microsoft account linked to your Microsoft 365 subscription.
If the issue still persists, to help narrow down the issue:
- Does Defender fail to open, or does it open but fail when you sign in? Please share the exact error message.
- Which Microsoft 365 subscription do you have?
Click "Add comment" to let me know.
Thanks!